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The FDA is said to have of late instituted a crack down on weight loss supplements as a result of very bad uncomfortable side effects and even death associated with some dietary supplements like ephedra. The ban on ephedra goods resulted to the roll-out of so-called ephedra free weight loss supplements, these too have been shown to yield their very own fair share of problems and they too could possibly be most likely going to a similar fate as ephedra.
These ephedra free medications have been shown to result in a boost in heart rate and a several other side effects on healthy men and women reported by a health specialist who participated in the research.
The inquiry performed by the University of California at Berkeley was the initial one to look into the health effects of reformulated weight loss supplements. On the list of things analyzed for included hypertension and heart beat rate of volunteers who were given reformulated weight loss supplements made out of extracts of bitter orange.
After the ban slapped on ephedra by FDA, an increasing sum of weight loss product manufactures have changed to extracts of bitter orange. The USB research required 20 healthy volunteers, who were given individual doses of a weight loss supplement or a placebo.
The diet supplements screened in the research project were Xenadrine EFX and Advantra Z, each of which contains bitter orange extracts. The used drug was shown to effect a slight increase in heart pulse rate all the way to 16 beats in one minute. The Thermogenic Xenadrine EFX in particular was shown to rev up heart rate by 13 per cent, something which makes it almost equivalent in performance to ephedra.
Bitter orange extracts contain synephrine, a ingredient present in over 90% of citrus fruits but found in increased concentrations in fruits such as Sour orange, Zhi shi and bitter orange and which happens to be widely used as a medication in the treatment of respiratory tract congestion and high blood pressure. Xenadrine EFX is known for a stimulant in the ingredient, usually caffeine. The quantity of caffeine is Xenadrine is estimated to be roughly the same as 3 coffee cups. This is the component to blame for the increase in blood pressure and individuals using this product are informed against over dosage.
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